Stock of the Day

December 23, 2022

Iovance Biotherapeutics (IOVA)

$5.00
+$0.34 (+7.3%)
Market Cap: $2.08B

About Iovance Biotherapeutics

Iovance Biotherapeutics, Inc., a commercial-stage biotechnology company, develops and commercializes cell therapies using autologous tumor infiltrating lymphocyte for the treatment of metastatic melanoma and other solid tumor cancers in the United States. The company offers Amtagvi, a tumor-derived autologous T cell immunotherapy used to treat adult patients with unresectable or metastatic melanoma; and Proleukin, an interleukin-2 product for the treatment of patients with metastatic renal cell carcinoma. It also develops lifileucel in combination with pembrolizumab to treat frontline advanced melanoma patients; LN-145 for the treatment of non-small cell lung cancer (NSCLC) and solid tumor cancers; IOV-4001, which is in Phase 1/2 IOV-GM1-201 clinical trial, for the treatment of NSCLC; and lifileucel for gynecological cancers. The company has collaborations and licensing agreements with WuXi Advanced Therapies, Inc.; National Institutes of Health; the National Cancer Institute; H. Lee Moffitt Cancer Center; The University of Texas M.D. Anderson Cancer Center; Cellectis S.A.; Novartis Pharma AG; and Boehringer Ingelheim Biopharmaceuticals GmbH. The company was formerly known as Lion Biotechnologies, Inc. and changed its name to Iovance Biotherapeutics, Inc. in June 2017. Iovance Biotherapeutics, Inc. was incorporated in 2007 and is headquartered in San Carlos, California.

Today's Trend

Iovance Biotherapeutics, Inc. (NASDAQ: IOVA) appears to be getting a modest lift from a batch of analyst estimate revisions that are mostly constructive for near-term profitability, even though some longer-dated forecasts were trimmed. The stock has also drawn attention from a Zacks comparison piece that highlighted Iovance’s commercial momentum and expanding Amtagvi pipeline as reasons it may be better positioned than peers.

  • Zacks Research raised its FY2026 earnings estimate for Iovance Biotherapeutics and also nudged up expectations for Q2 2026, Q1 2027, Q2 2027, and Q1 2028, suggesting improving near-term outlook and some progress toward narrowing losses.
  • A Zacks article argued that Iovance’s commercial momentum and expanding Amtagvi pipeline make it look better positioned than Agenus, which may support investor sentiment around the company’s growth story. Article Title
  • Analysts still expect Iovance to post losses across the forecast period, including a consensus full-year loss estimate of about $0.63 per share, so the company remains a turnaround story rather than a profitable one.
  • Zacks Research lowered several longer-term estimates, including Q3 2026, Q4 2026, Q3 2027, Q4 2027, and FY2028, which may temper enthusiasm by implying a slower earnings recovery farther out.

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