Stock of the Day

December 16, 2021

Zentalis Pharmaceuticals (ZNTL)

$2.14
-$0.10 (-4.5%)
Market Cap: $153.73M

About Zentalis Pharmaceuticals

Zentalis Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing small molecule therapeutics for the treatment of various cancers. Its products candidatures include the ZN-c3, an inhibitor of WEE1, a protein tyrosine kinase for the treatment of inhibitor for advanced solid tumors and hematological malignancies; in Phase 2 clinical trial as a monotherapy for the treatment of uterine serous carcinoma indications; Phase 2 clinical trial in Cyclin E1 driven high-grade serous ovarian cancer, fallopian tube, or primary peritoneal cancer; Phase 1/2 clinical trial in combination with PARPi for platinum-resistant ovarian cancer; Phase 1b clinical trial in combination with chemotherapy in platinum-resistant ovarian, and peritoneal or fallopian tube cancer; Phase 1/2 clinical trial in combination with chemotherapy in relapsed or refractory osteosarcoma; Phase 1/2 clinical trial with encorafenib and cetuximab for mutant metastatic colorectal cancer; and Phase 1/2 clinical trial in combination with chemotherapy in pancreatic cancer. The company's products pipeline also includes ZN-d5, an oral small molecule inhibitor of B-cell lymphoma 2, for hematological malignancies and related disorders; and BCL-xL heterobifunctional degrader, a member of the anti-apoptotic BCL-2 proteins, for solid tumors and hematological malignancies. Zentalis Pharmaceuticals, Inc. has licensing agreements and strategic collaborations with Recurium IP Holdings, LLC; Pfizer, Inc.; Zentera Therapeutics; Dana-Farber; and GlaxoSmithKline plc. The company was incorporated in 2014 and is headquartered in New York, New York.

Today's Trend

Zentalis Pharmaceuticals, Inc. (NASDAQ: ZNTL) shares have recently been volatile as investors weigh a bullish analyst upgrade against a more cautious broader analyst view and the company’s upcoming cancer-data catalyst.

  • Leerink upgraded Zentalis to Outperform and set an $8 price target, replacing its Market Perform rating. Based on the referenced price of $2.67, the target implies approximately 200% upside, providing a significant boost to investor sentiment. Leerink upgrades Zentalis Pharmaceuticals to Outperform
  • The upgrade helped drive a sharp near-term rebound in ZNTL shares, with coverage noting that the stock gained more than 10% following Leerink’s recommendation. Zentalis stock gains after Leerink upgrade
  • Investors are also looking ahead to October cancer data, which could provide an important readout for Zentalis’ clinical pipeline and serve as a near-term catalyst if results support the company’s drug-development prospects. Zentalis heads toward October cancer data
  • Wells Fargo maintained a Hold rating, while the broader brokerage consensus remains Hold. This limits the strength of the bullish signal from Leerink and highlights continued uncertainty around Zentalis’ clinical and financial outlook. Wells Fargo gives Zentalis a Hold rating
  • Zentalis remains a speculative biotech, with shares still well below their 50-day and 200-day moving averages. The company also recently reported a quarterly loss that exceeded analysts’ expected loss, reinforcing concerns about execution and the need for positive clinical results.